Flavin Hydroperoxide: New tricks from an old dog

Since its discovery, in the early 1930s, the chemistry of riboflavin has been studied in great detail. It is therefore surprising that several new flavin-mediated reactions have been discovered over the past few years. My lecture will focus on three reactions where riboflavin is used as a substrate in a biosynthetic pathway. These reactions are involved in riboflavin catabolism, Vitamin B₁₂ biosynthesis and roseoflavin biosynthesis.