Skip to main content
Skip to main menu Skip to spotlight region Skip to secondary region Skip to UGA region Skip to Tertiary region Skip to Quaternary region Skip to unit footer


Structure-elucidation from ion mobility spectrometry-mass spectrometry data: are detailed structures amenable?

Christian Bleiholder
Florida State University
Chemistry Building, Room 400
Physical Seminar

Ion mobility spectrometry-mass spectrometry (IMS-MS) methods have gained significant attention to study structures for complex and dynamic biological systems such as amyloid assemblies or viral capsids. These studies make use of the fact that the measured mobility of an ion is related to its microscopic structure. However, current studies do not allow a quantitative and predictive structural interpretation of IMS-MS data. In this contribution, we discuss our approach towards a quantitative and predictive structural interpretation of IMS-MS data. Specifically, we present our progress made towards conducting two-dimensional, time- and energy-resolved trapped ion mobility spectrometry measurements (TIMS/TIMS) and discuss approaches for accurately computing ion mobility spectra for structural analysis.

Support Us

We appreciate your financial support. Your gift is important to us and helps support critical opportunities for students and faculty alike, including lectures, travel support, and any number of educational events that augment the classroom experience. Click here to learn more about giving.

Every dollar given has a direct impact upon our students and faculty.

Got More Questions?

Undergraduate inquiries: 

Registration and credit

AP Credit, Section Changes, Overrides,

Graduate inquiries:

Contact Us!

Assistant to the Department Head: Donna Spotts, 706-542-1919 

Main office phone: 706-542-1919 

Main Email:

Head of Chemistry: Prof. Jason Locklin