Tags: Analytical Seminar

Nowadays, ion mobility is getting more and more popular due to its ability to add an additional degree of separation when coupled with traditional techniques like liquid or gas chromatography along with providing key information for a molecule’s collision crosssection (CCS). CCS is a measurement of a molecule’s effective area when it is allowed to collide with a neutral gas such as Helium or Nitrogen under the influence of an electrical current…
In response to environmental stress, living organisms are known to actively alter their membrane lipid compositions in their cell membranes to maintain cellular function and integrity. Glycerophospholipids, a main component of bacterial and human cell membranes, consist of a phosphate headgroup, glycerol backbone, and two fatty acids chains attached at either the sn-1 or sn-2 positions. Recent studies revealed the shift in the relative…
In recent years, significant efforts have been focused into understanding metabolic reprogramming in cancer with the hope of discerning context-specific biology that is exploitable for either for diagnosis or treatment. While some generalized phenomena such as the ‘Warburg Effect’ have been identified, the metabolic landscape of cancer is highly heterogeneous, as tumors from the same sub-type can exhibit vastly different metabolic profiles,…
While there has been a recent emphasis in the field of chemistry education research on bridging the gap between research and practice, another important divide warrants attention: the growing gap between undergraduate academia and chemical industry. According to recent American Chemical Society data, approximately 70% of chemistry graduates enter industry directly after earning their bachelor’s degree. However, little is known about how these…
Techniques for the detection of extremely high mass ions or the analysis of heterogenous samples in mass spectrometry are often limited by overlapping charge states and poor resolution.1 The invention of electrospray ionization allowed for ionization of increasingly larger ions in mass spectrometry where multiple charging allows for the mass-to-charge ratio to be much lower than the molecular mass.2 In traditional mass spectrometry, the mass-to-…