Tags: Analytical Seminar


Particle Surface Modification for Improved Properties and Applications

Advancing requirements for composites having enhanced chemical, mechanical and physical properties are being met by molecular modifications of  both  filler particles and the matrix they are placed in. The presenter has enjoyed making successful contributions to a wide variety of technical problems by employing various chemical principles for particle synthesis and surface modification. Both synthetic and physical chemical deposition…


Bio-Responsive Polyrotaxane-Based Nanochelators for Improving Transfusional Iron Chelation Therapy

Iron overload (IO) is one of the most common genetic diseases in the U.S. but individuals with the condition typically exhibit few symptoms in the early stages and are often unaware of their condition until it has already progressed to a dangerous level. Untreated, IO can induce cirrhosis and increase risk of liver cancer, cause arthritis, or lead to impotence. Recent studies have furthermore consistently demonstrated the presence of excess iron…


Hair Reveals what People Conceal: Biometric Traits from the Chemical Analysis of Human Hair

This presentation reveals the profound ways in which isotope ratio mass spectrometry (IRMS) can provide information about the geographic origin and history of almost everything around us, including our fellow humans. The presentation explains the ways in which we are and are not exactly what we eat, and it explains how researchers use IRMS measurements of hair to determine the geographic origin and travel histories of animals and humans.…


A methodological perspective on the reactivity of organic carbon in the sea

The oceans contain the largest proportion of carbon atoms that participate in biogeochemical cycles on Earth's surface over timescales ranging from less than a second to thousands of years.  Radiocarbon (14C) measurements suggests that most (~95 %) of the carbon atoms bound within organic molecules in seawater can persists for thousands of years.  The abundances of these atoms at each time and place in the ocean are complete records of…


Rapid and Robust Photochemical Attachment of Functional Polymer Films to Alkyl Surfaces via Benzophenone Crosslinking


Developing Ultrasensitive Library-Aliquot-based Droplet Digital PCR for detecting T790M

Patients with non-small cell lung cancer (NSCLC) harboring activating mutations in the epidermal growth factor receptor (EGFR) show significant progression-free survival benefit when they are treated with EGFR tyrosine kinase inhibitors (TKIs), have been recommended as the first-line therapy for NSCLC patents with EGFR-sensitizing mutations.1 Unfortunately, the vast majority acquire resistance after 9-12 months of treatment. However, the…


Living Single-Cell Real Time Imaging via Plasmonic-Enhanced Rayleigh & Raman Spectroscopy

Single-cell analysis is an active research area focused on deciphering cellular processes from a single living cell.1 Various crucial biological phenomena are either invisible or only partially characterized when analyzed with standard techniques that utilize bulk cell populations or entire tissues. This is due to the high level of heterogeneity within cell cultures.1-3 To provide novel insight into these diverse biological properties specific…


TBA


Fabric Phase Sorptive Extraction on Emerging Contaminants in Environmental Waters

Emerging contaminants in water is a major focus of many environmental and public health organizations worldwide.1-2 Specifically, emerging contaminants of concern are pharmaceuticals such as over the counter drugs, hormonal supplements, and veterinary medicines. It is known that trace amounts of these chemicals are present in drinking water and in surface water. These chemicals have adverse effects on wildlife and the subsequent ecosystems, and…


Versatile Polymer-based Glycosurface Fabrications for Gliding Motility of Mycoplasma Pneumoniae

Glycopolymer is an important class of synthetic molecules that emulate many biological and structural characteristics of cell-surface glycoproteins or glycolipids. Here, a general and versatile strategy is reported for the fabrication of glycopolymer-modified substrates that ligates reducing glycans toward polymeric scaffold through hydrazide linker.1 The fabrication process and conjugation proceeded in mild conditions with good ligation…
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