Tags: Analytical Seminar


Multi electrode harmonized Kingdon traps as mass analyzers for FT based mass spectrometers

Kingdon trap [1] is the simplest ion trap consisting of wire and cylindrical electrode surrounding with different potential.  Well-known Orbitrap [2], has emerged as development of R. D. Knight’s idea [3], who modified the cylinder electrodes geometry to make the field inside Kingdon trap quadratic (harmonic) and proposed measuring the frequencies of ions oscillating in such field by resonant excitation of their motion along trap axis, to…


Giant Magnetoresistance Based Spin Valve Sensor for Biomolecule Detection

Ever since its discovery in 1988 by two research groups in France and Germany, Giant Magnetoresistance (GMR) has revolutionized the application of magnetic sensors in hard disk drives and magnetic memories.1,2 It also offers an inspiration for their use in magnetic biodetections, a growing field with great promises. One of them is the spin valve (SV) sensor, a magnetic field sensor sensing the magnetic fringing field of captured magnetic…


TBA


TBA


Characterization of Hydrophilic Post Translational Modifications by LC-MS

Post Translational Modifications (PTM) are modifications which take place following protein biosynthesis. There are hundreds of PTMs which have been discovered and possibly many more which have yet to be discovered. The analysis of the 20 amino acids to study has exponentially increased to seemingly limitless combinations of proteins and PTMs, and this number of possible PTM combinations add daunting challenges for proteomic analysis. The most…


Interaction between heparan sulfate and the Roundabout receptor at the single-molecule level

Scanning probe microscopy methodologies have advanced to the point that in situ measurements of complex biological systems can be routinely measured at the single-molecule level1, providing information on rare states that can be lost in standard ensemble measurements2and allowing highly specific detection of various proteins and polysaccharides3,4. One such system that has attracted considerable attention is that of the cell signaling pathway…


Chemical exchange and saturation transfer (CEST) based magnetic resonance imaging (MRI)


Nanoparticle Synthesis using Shock Tubes


Analysis of Water and Soil Samples using Portable Instruments

The Environmental Protective Agency (EPA) monitors and regulates harmful chemical contaminants in the environment in order to reduce the detrimental effects they have on people and the environment. In order to monitor these contaminants, specifically in water and/or soil, people are required to go to the location of interest and collect samples to bring back to a laboratory to be analyzed. This process requires samples to be stored and preserved…


Iodine Based Nanotherapeutics

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