Date & Time: Feb 16 2023 | 11:10am Location: iSTEM Building 2, Room 1218 C−H activation has gained extensive attention as a powerful tool in synthetic organic chemistry. The carboxylate moiety is believed as a promising candidate, however, the C−H activation of carboxylic acid is highly challenging because of its weak directing ability. In recent years, the development of novel palladium catalysis strategies allows the utility of aliphatic acid in C(sp3)−H functionalization, and notably lactonization has displayed great compatibility. In this seminar, we will highlight three lactonization works by Jin-Quan Yu, who has made outstanding contribution to the palladium catalysis strategy, as well as other people's reports. References Zhuang, Z.; Yu, C.-B.; Chen, G.; Wu, Q.-F.; Hsiao, Y.; Joe, C. L.; Qiao, J. X.; Poss, M. A.; Yu, J.-Q. J. Am. Chem. Soc. 2018, 140, 10363 Zhuang, Z.; Yu, J.-Q. Nature 2020, 577, 656. Xu, L.-P.; Zhuang, Z.; Qian, S.; Yu, J.-Q.; Musaev, D. G. ACS Catal. 2022, 12, 4848 Chan, H. S. S.; Yang, J.-M.; Yu, J.-Q. Science 2022, 376, 1481 Type of Event: Organic Seminar Yizhi Cui Department: Graduate Student, Department of Chemistry University of Georgia Learn more about the speaker https://chem.uga.edu/directory/people/yizhi-cui
